Cell Normalization Technology for High Content Screening :
The glass coverslip format with an array of over
10.000 micropatterns and a printed grid for easy localization.
Sensitivity & powerful quantification to cell-based assays and screening
Cell basedassay¸¦À§ÇÑ New Micropattern Chip
144 micropatterns in 2cm
x 2cm,170um thick gridded
coverslip of glass
5 shapes (Disk, Crossbow, H, Y, L)
and 3 sizes (large,
medium,small)
Straightforward analysis, reliable results and faster discovery
-
Reduce cell to cell variability
-
Control the position of cell compartments and protein networks
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Achieve simple and rapid image analysis
-
Map a "standard" averaged cell and use it as a reference
The CYTOO technology offer a whole range of new possibilities for
the scientist.
and some applications have already been well established,
others are developing
Easy analysis of cell
contractility in response to drugs
CYTOO
Microfludic's Theory :
In
standard culture conditions
(left), the shape and extent
of the Golgi
apparatus (in red) vary
extensively with cell shape.
On micropatterns
(right), the shape and positioning
of the Golgi apparatus
is identical in all cells
(Dimitrov, Thery, Bornens).
CYTOO
chips are packaged in an embossed
clear plastic
6 blister tray sealed with paper.
In this format
CYTOO chips may be loaded directly
into a 6 well
plate with no direct manipulation.
The CYTOO
chamber uses a patented magnetic system (from
Live Cell
Instruments) for easy assembly.
The CYTOOchamber has the same
footprint as standard 35mm culture dishes and therefore will fit into all
35mm microscope stage adaptors.
CYTOOchambers are available in 1well and 4well formats. We are currently
updating our store to include the 4well
CYTOO PLATETM
Microfludic multiwell
Plate :
The
standard glass bottom microplate format presenting thousands of micropatterns
per well.
CYTOOplates are ideal for pharma, biotech and academic
screening center customers employing high content cell-
based assays for research, drug safety, and drug screening applications
- Glass-bottom microplates
- 96, 384-well format
- Structures for fluorescence applicationswith reduced background and minimum
scattered light.
- Over 3,000 micropatterns. / well
A
new dimension to your HCA/HCS assays:
? -
Powerful assay standardization -
Reproducible & sensitive cell phenotype
quantification -
Straightfoward image Analysis
Columns 1 and 12
are homo- geneously
covered with adhesive
protein
where your cells
will behave as
if they were on
a conventional cell
culture surface.