BIOLOGICS
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Ultrasonic Homogenizer Series
(Sonicators)
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For
over
five
decades,
BioLogics
laboratory
equipment
has
been
setting
new
standards
for
design
innovation,
performance,
and
reliability.
The BioLogics family of Ultrasonic
Homogenizers offer precision engineering with all the
features
necessary to create a total system for ultrasonic disruption.
The
Ultrasonic Homogenizers can disintegrate most cells, bacteria,
spores or tissue.
They can prepare an emulsion down to 1/100 of a micron
homogenize "immiscible" liquids, accelerate enzymatic and chemical reactions,
stimulate bacterial activity, disperse solids in liquids and degas liquids
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Features
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How it Works :
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•
The ultrasonic power supply transforms line voltage to high frequency 20 kHz electrical energy. •
This electrical energy is transmitted to the probe where it is converted to mechanical energy. •
The vibrations from the probe are coupled to and intensified by the titanium tip. •
The probe vibrates in a longitudinal direction and transmits this motion to the titanium tip immersed in the solution. •
Cavitation results, in which microscopic vapor bubbles are formed momentarily and implode, causing powerful
infinitesimal shock waves to radiate throughout the solution in proximity to the radiating face of the tip.
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Contact
vs.
Non-Contact
Homogenization
Methods
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The
CONTACT
homogenization
is
the
most
common
method
of
processing
a
sample.
The
probe
is
immersed
into
the
sample
where
the
radiating
face
of
the
probe
causes
the
sample
to
cavitate,
quickly
processing
the
sample.
Small
diameter
probes
such
as
the
Stepped
and
Tapered
Micro
tips
generate
high
intensity
cavitation
and
are
utilized
when
processing
small
volume
samples.
Large
diameter
probes
such
as
the
Solid
and
Tapped
tips
generate
low
intensity
cavitation
and
are
utilized
when
processing
large
volume
samples.
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The
NON-CONTACT
homogenization
method
is
utilized
when
processing
small
volume
samples
where
the
probe
does
not
contact
the
sample.
This
method
is
sometimes
referred
to
as
a
“high
intensity
ultrasonic
bath”.
The
cavitation
within
the
water
processes
the
micro
tubes
or
vessels
which
are
suspended
during
processing.
Non-contact
method
is
most
effective
for
volumes
less
than
250
μl
as
foaming
or
sample
loss
are
eliminated.
In
addition,
this
method
ensures
that
sterile
or
pathogenic
samples
are
not
aerosolized
preventing
cross
contamination
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Automatic Tuning :
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All the of our Ultrasonic Homogenizers models employ a propriety feedback system, insuring that the generator is always working at it
maximum efficiency regardless of the application. There is no need for constant adjustment by the operator.
The percentage of ultrasonic power emitted is indicated by the output LED meter,
enabling accurate reproducible results. |
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Applications :
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- Accelerate Enzymatic Reactions
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- Accelerate Chemical Reactions
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- Stimulate Bacterial Activity
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Models
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Catalogue
number
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0-121-0002
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Descriptions
The Model 150V/T Ultrasonic
Homogenizer offers precision engineering with all the features necessary to
create a total system for 150 watts of ultrasonic disruption.
Functions
PULSER POWER MODE – This allows the sample to be processed at full power while
limiting
temperature
increase and is essential for heat sensitive
samples. CONSTANT POWER MODE – Selectable for non-heat critical sample
applications. With
0-100%
Amplitude
(Power)
control,
the
operator
can
optimize
the
titanium
probe’s
intensity
to
efficiently
process
the
sample.
TIMER – 1 to 15 minutes
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includes:
-
ultrasonic generator
- transducer assembly
- stainless steel
transducer post - laboratory clamp - 3 prong transducer clamp - pair of pin
wrenches
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Specifications |
PROCESSING VOLUME
|
250 µl - 300 ml |
TIMER
|
1 - 15 MINUTES |
MAX. TIP DIAMETER
|
1/2" (12.7mm) |
PULSER
|
10 - 90% |
POWER OUTPUT
|
0 - 150 WATTS |
DISPLAY TYPE
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LED
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OUTPUT FREQUENCY
|
20 kHz |
MICRO
PROCESSING
CONTROL
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N/A
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AUTOMATIC TUNING
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YES |
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OPTIONAL
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Catalogue
number
:
0-122-0002
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Descriptions
The Model 300V/T Ultrasonic
Homogenizer offers precision engineering with all the features necessary
to
create a total system for 300 watts of ultrasonic disruption.
Functions
PULSER POWER MODE – This allows the sample to be processed at full power while
limiting
temperature
increase and is essential for heat sensitive
samples. CONSTANT POWER MODE – Selectable for non-heat critical sample
applications.
With
0-100%
Amplitude
(Power)
control,
the
operator
can
optimize
the
titanium
probe’s
intensity
to
efficiently
process
the
sample. TIMER – 0 to 15 minutes
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includes:
-
ultrasonic generator
- transducer assembly
- stainless steel
transducer post - laboratory clamp - 3 prong transducer clamp - pair of pin
wrenches
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Specifications |
PROCESSING VOLUME
|
250 µl - 2000 ml |
TIMER
|
1 - 15 MINUTES |
MAX. TIP DIAMETER
|
1" (25.4mm)/Cup
Tip |
PULSER
|
10 - 90% |
POWER OUTPUT
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0 - 300 WATTS |
DISPLAY TYPE
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LED
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OUTPUT FREQUENCY
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20 kHz |
MICRO
PROCESSING
CONTROL
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N/A
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AUTOMATIC TUNING
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YES |
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OPTIONAL
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Catalogue
number
:
0-127-0002
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Descriptions
The Ultrasonic 3000 Ultrasonic
Homogenizer delivers 300 watts of ultrasonic disruption and includes
an
integrated Sound Abating Chamber to reduce cavitational sound emitted during
processing. The clear door permits viewing of the sample while processing. An access port
for cables and tubing
is also provided for use with Cup Tips and the Continuous
Flow Chamber
Functions
PULSER POWER MODE – This allows the sample to be processed at full power while
limiting
temperature
increase and is essential for heat sensitive
samples. CONSTANT POWER MODE – Selectable for non-heat critical sample
applications.
With
0-100%
Amplitude
(Power)
control,
the
operator
can
optimize
the
titanium
probe’s
intensity
to
efficiently
process
the
sample. TIMER – 0 to 15 minutes
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includes:
-
sound abating chamber with adjustable height sample table - transducer assembly
-
pair of pin wrenches
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Specifications |
PROCESSING VOLUME
|
250 µl - 2000 ml |
TIMER
|
1 - 15 MINUTES |
MAX. TIP DIAMETER
|
1" (25.4mm)/Cup
Tip |
PULSER
|
10 - 90% |
POWER OUTPUT
|
0 - 300 WATTS |
DISPLAY TYPE
|
LED
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OUTPUT FREQUENCY
|
20 kHz |
MICRO
PROCESSING
CONTROL
|
N/A
|
AUTOMATIC TUNING
|
YES |
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INTEGRATED
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Catalogue
number
:
0-128-0002
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Descriptions
3000MP Ultrasonic Homogenizer delivers 300 watts of ultrasonic
disruption with precision control from
a microprocessor and a graphical user
interface displayed on a large bright 5.7" (145 mm) LCD display. The integrated Sound Abating Chamber reduces cavitational sound emitted
during sample processing.
The clear door permits viewing of the sample while
processing. An access port for cables and tubing is
also provided for use with
Cup Tips and the Continuous Flow Chamber.
With
0-100%
Amplitude
(Power)
control,
the
operator
can
optimize
the
titanium
probe’s
intensity
to
efficiently
process
the
sample.
Functions
MANUAL MODE – the user defines
the AMPLITUDE, can enable the PULSER feature, and monitor sample temperature
during processing. PROGRAM MODE – the user can define, store, and recall up to 10 programs.
Within each PROGRAM,
the AMPLITUDE, PULSER parameters, TEMPERATURE settings for
COOL DOWN
and SHUT DOWN temperatures,
can be defined and stored.
MACRO MODE
– the user to assemble up to 8 sequences using any of the
10 stored PROGRAMS with
an optional user defined time delay, from 1 secs to 99
hrs, between each sequence.
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includes:
-
Ultrasonic generator with
integrated sound abating
chamber with adjustable
height sample table - transducer assembly - temperature probe
-
pair of pin
wrenches
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Specifications |
PROCESSING VOLUME
|
250 µl - 2000 ml |
TIMER
|
1
SEC - 99
HOURS |
MAX. TIP DIAMETER
|
1" (25.4mm)/Cup
Tip |
PULSER
|
1
SEC - 1
HOUR |
POWER OUTPUT
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0 - 300 WATTS |
DISPLAY TYPE
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5.7” (145mm)GLCD
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OUTPUT FREQUENCY
|
20 kHz |
MICRO
PROCESSING
CONTROL
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YES
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AUTOMATIC TUNING
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YES |
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INTEGRATED
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Probe
Tips & Accessories
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Micro
Tip
Probes
300
μl
to
25
ml
Sample
Volumes
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Micro Tips are
narrow
and
long
probes
which
generate
high
intensity
cavitation
for
processing
small
sample volumes.
The
Stepped
Micro
Tip
probe
is
coupled
directly
to
the
Transducer.
The
Tapered
Micro
Tip
probes
are
threaded
to
the
1/2”
(12.7
mm)
Tapped
Tip
probe
(0-120-0010)
then
coupled
to
the
Transducer.
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Solid
Tip
Probes
5
ml
to
2000
ml
Sample Volumes
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Solid
Tip
probes
are
manufactured
from
a
titanium
alloy
and
machined
to
a
specific
diameter
and
shape.
When
coupled to
the
Transducer,
the
probe
is
driven
to
its
resonant
frequency,
causing
the
probe
to
expand
and contract
longitudinally.
When
the
probe
is
immersed
into
a
liquid
sample,
the
cavitation
formed
processes
the
sample.
Solid
Tip
probes
should
be
utilized
when
processing
liquids
containing
organic
solvents
or
high
surface
tension
samples.
In
addition,
Solid
Tip
probes
are
machined
from
one
solid
titanium
piece
and
less
likely
to
cause
sample cross contaminations. Sample
volume
is
determined
by
the
tip
diameter.
Smaller
diameter
probes
generate
high intensity
cavitation
in
a
small
focused
area,
ideal
for
small
sample
volumes.
Larger
diameter
probes
generate
low intensity
cavitation
in
a
broader
area,
ideal
for
larger
sample
volumes.
The
radiating
face
or
flat
portion
of
the
probe will
pit
or
erode
in
time
and
should
be
replaced
when
worn.
Probe
performance
degrades
in
proportion
to
the
degree
of
erosion
or
pitting
which
occurs
at
the
tip
surface,
until
a
point
is
reached
where
the
level
of
energy
transmitted
in
the
sample
is
significantly
lessoned.
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SOLID
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SOLID
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SOLID
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SOLID
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Tapped
Tip
Probes
10
ml
to
2000
ml
Sample
Volumes
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Tapped
Tip
probes
are
a
2
piece
design
comprised
of
the
Body
and
Flat
Tip,
both
manufactured
from
a
titanium
alloy
and
machined
to
a
specific
diameter
and
shape.
The
body
has
a
threaded
end
allowing
the
flat
tip
to
be
replaced.
The
flat
tip
or
radiating
face
will
pit
or
erode
in
time
and
should
be
replaced
when
worn.
Probe
performance
degrades
in
proportion
to
the
degree
of
erosion
or
pitting
which
occurs
at
the
tip
surface,
until
a
point
is
reached
where
the
level
of
energy
transmitted
in
the
sample
is
significantly
lessoned. Tapped
Tip
probes
are
NOT
recommended
when
processing
liquids
containing
organic
solvents
or
high
surface
tension
samples.
Utilizing
Tapped
Tip
probes
with
such
samples
are
likely
to
cause
sample
cross
contaminations.
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Extender
Tip
Probes
Solid
and
Tapped
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Extender
Tips
are
utilized
to
extend
the
length
of
a
probe
to
reach
into
long
necked
vessels.
They
attach
to
the
corresponding
diameter
Tapped
Tip
probes
and
generally
increase
the
overall
length
by
5” (127
mm).
Extender
Tips
offer
the
same
sample
volume
and
amplitude
as
their
corresponding
diameter
Tapped
Tip
probes.
Extender
Tips
are
available
in
Solid
to
Tapped
configurations.
Tapped
Extender
Tips
use
the
corresponding
diameter
replacement
Flat
Tips.
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Titanium Solid Extender Tips
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Titanium Tapped Extender Tips
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Catalog No.
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TIP DIA.(MM)
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LENGTH(CM)
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TYPE
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SOLID
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SOLID
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SOLID
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Flat
Tips
Replaceable
tips
for
Tapped
Tips
Probes
and
Tapped
Extender
Tips
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Tapped
Tip
and
Extender
Tip
probes
use
replaceable
Flat
Tips.
During
normal
use,
the
radiating
face
or
Flat
Tip
of
the
probes
erodes
and
becomes
less
effective
over
time.
Replace
Flat
Tips
with
corresponding
Tapped
Tip
or
Extender
Tip
diameter.
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CUP
Tips
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The
Cup
Tip
offers
non-contact
homogenization
of
small
volume
samples
in
a
high
intensity
ultrasonic
bath.
Samples
are
processed
in
sealed
tubes
or
vials
eliminating
aerosols
and
cross
contamination.
Multiple
tubes
or
vials
of
sterile
or
pathogenic
samples
can
be
processed
simultaneously.
The
titanium
probe
is
mounted
within
an
acrylic
body
where
the
body
is
filled
with
water.
Sample
tubes
or
vials
can
be
placed
in
the
tray
and
suspended
above
the
probe
during
processing.
The
cavitation
in
the
water
processes
the
tubes
or
vials.
During
sample
processing,
heated
is
generated,
so
inlets
with
barbed fittings
can
be
connected
to
cold
water
or
a
Chiller
to
maintain
temperature
and
water
level
within
the
acrylic
body.
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0-120-0020
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Chamber
Vol
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250
ml
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Intensity
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Medium
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Continuous
Flow
Chamber
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The
Continuous
Flow
Chamber
permits
in
line
or
continuous
processing
of
large
volume
batch
samples.
Batch
sample
volumes
can
be
recirculated
through
the
chamber
multiple
times
for
desired
sample
results.
Samples
are
passed
through
the
chamber
using
one
of
the
two
bottom
inlets.
As
the
sample
flows
through
the cavitation
chamber,
the
sample
is
processed.
The
processed
sample
exits
the
chamber
through
the
two outlet
ports.
By
recirculating
the
sample,
adjusting
flow
rate
and
cavitation
intensity,
the
desired
results
can
be
achieved.
During
sample
processing,
heated
is
generated
by
the
probe.
Connecting
the
integrated
cooling
jacket
to
a
cold
water
source
or
Chiller,
will
maintain
sample temperature
during
processing.
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Catalog No.
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0-120-0026
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Material
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Stainless
Steel
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Oper
Pressure
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20
psi
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Internal
Vol
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35
ml
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*
REQUIRES
THE
3/4”
(19.1
mm)
DIAMETER
SOLID
TITANIUM
TIP
CATALOG
NO.
0-120-0013
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SONABOX
Sound
Abating
Chamber
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The
SONABOX
sound
abating
chamber
reduces
cavitational
sound
emitted
during
processing
when
used
in
conjunction
with
the
Model
150VT
and
300
VT
Ultrasonic
Homogenizers.
Harmonics
are
produced
by
the
vessel
walls
and
fluid
surface,
and
can
be
discomforting
to
the
user
with
extended
operation.
The
SONABOX
reduces
the
harmonics
by approximately
20-25
dBa.
The
clear
acrylic
door
permits
viewing
of
the
sample
while
protecting
the
operator
against
accidental
splashing.
The
height
of
the
sample
table
can
be
adjusted
to
vessel
size
and
shape.
Access
ports
for
cables
and
tubing
are
also
provided
for
use
with
the
Cup
Tip
or
Continuous
Flow
Chamber
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Catalog No.
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0-125-0001
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Sample
Table
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Adjustable
Height
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Chamber
Doo
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Clear
Acrylic
Door
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Cable
&
Tubing
Ports
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2
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Outside
|
26.7
cm
W
x
21.6
cm
D
x
59.7
cm
H
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Inside
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24.8
cm
W
x
19.7
cm
D
x
45.1
cm
H
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Small
Volume
Probe
Map
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No.
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VOLUME
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DESCRIPTION
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CATALOG
NO
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①
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-
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Transducer
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2-122-0010
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②
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Based
on
tube
vol
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Cup
Tip
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2-122-0019
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③
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-
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Microtube
Tray
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2-120-0021
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④
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300ul~15ml
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5/32"(3.9mm)Stepped
Micro
Tip
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2-120-0005
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⑤
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250ul~10ml
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1/8"(3.2mm)
Tapered
Micro
Tip
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2-120-0007
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⑥
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750ul~25ml
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3/16"(4.8mm)Tapered
Micro
Tip
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2-120-0008
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⑦
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5ml~200ml
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3/8"(9.5mm)Solid
Tip
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2-120-0009
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⑧
|
10ml~300ml
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1/2"(12.7mm)Tapered
Tip
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2-120-0010
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⑨
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1/2"(12.7mm)Flat
Tip
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2-120-0016
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Large
Volume
Probe
Map
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No.
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VOLUME
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DESCRIPTION
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CATALOG
NO
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①
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-
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Transducer
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2-122-0010
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②
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10ml~300ml
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1/2"(12.7mm)Solid
Tip
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2-122-0011
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③
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10ml~300ml
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1/2"(12.7mm)Tapped
Tip
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0-120-0010
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④
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-
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1/2"(12.7mm)Flat
Tip
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2-120-0016
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⑤
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10ml~300ml
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1/2"(12.7mm)Solid
Extender
Tip
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0-120-0032
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⑥
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10ml~300ml
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1/2"(12.7mm)Tapped
Extender Tip
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2-122-0033
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⑦
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25ml~600ml
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3/4"(19.1mm)Solid
Tip
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0-120-0013
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⑧
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25ml~600ml
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3/4"(19.1mm)Tapped
Tip
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2-122-0012
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⑨
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-
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3/4"(19.1mm)Flat
Tip
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0-120-0017
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⑩
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25ml~600ml
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3/4"(19.1mm)Solid
Extender
Tip
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2-122-0016
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⑪
|
25ml~600ml
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3/4"(19.1mm)Tapped
Extender
Tip
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0-122-0016
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⑫
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50ul~2000ml
|
1"(25.4mm)
Solid
Tip
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2-122-0015
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⑬
|
50ul~2000ml
|
1"(25.4mm)
Tapped Tip
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0-122-0014
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⑭
|
-
|
1"(25.4mm)
Flat
Tip
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2-122-0018
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⑮
|
50ul~2000ml
|
1"(25.4mm)
Solid
Extender
Tip
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0-120-0036
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⑯
|
50ul~2000ml
|
1"(25.4mm)
Tapped Extender
Tip
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0-122-0037
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⑰
|
0.25L/min
|
Continuous
Flow
Chamber
|
0-120-0026
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SONABOX
Sound
Abating
Chamber
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250ml
Cup
Tip
and
8
position
Micro
Tube
Tray
shown
attached
to
transducer
assembly
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Continuous
Flow
Chamber
with
3/4'
Dia.
Solid
Titanium
Tip
and
Tranducer
assembly
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